国产日韩综合无码精品,天天性爱综合网性色av

中文名稱

胰島素樣生長因子1抗體

別名

IBP1; IGF 1; IGF I; IGF-1;IGF IA; IGF IB; IGF1; IGFI; IGFIA; Insulin like growth factor 1 (somatomedin C); Full=Insulin-like growth factor I; Insulin Like Growth Factor 1; Insulin like growth factor IA; Insulin like growth factor IB; Mechano growth factor; MGF; Mechano growth factor; MGF; Somatomedia C; Somatomedin C; IGF1_HUMAN.

研究領(lǐng)域

細胞生物發(fā)育生物學(xué) 信號轉(zhuǎn)導(dǎo) 生長因子和激素糖尿病

抗體來源

Rabbit

克隆類型

Polyclonal

交叉反應(yīng)

Human, Rat, (predicted: Mouse, Dog, Pig, Cow, Rabbit, Sheep, )

產(chǎn)品應(yīng)用

WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分子量

7.7/21kDa

細胞定位

分泌型蛋白

性狀

Liquid

濃度

1mg/ml

免疫原

KLH conjugated synthetic peptide derived from human IGF I:108-195/195

亞型

IgG

純化方法

affinity purified by Protein A

儲存液

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存條件

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMed

產(chǎn)品介紹

The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]

Function:
The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake.

Subcellular Location:
Secreted.

DISEASE:
Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) [MIM:608747]. IGF1 deficiency is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation.

Similarity:
Belongs to the insulin family.

SWISS:
P05019

Gene ID:
3479

Database links:

Entrez Gene: 3479 Human

Omim: 147440 Human

SwissProt: P05019 Human

Unigene: 160562 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

胰島素樣生長因子1(IGF-1)是一種生長調(diào)節(jié)激素，由肝分泌并入血液循環(huán)的中性多肽，具有調(diào)節(jié)生長和代謝、胰島素樣及促細胞分裂的活性。

英文名稱	IGF I
中文名稱	胰島素樣生長因子1抗體
別名	IBP1; IGF 1; IGF I; IGF-1;IGF IA; IGF IB; IGF1; IGFI; IGFIA; Insulin like growth factor 1 (somatomedin C); Full=Insulin-like growth factor I; Insulin Like Growth Factor 1; Insulin like growth factor IA; Insulin like growth factor IB; Mechano growth factor; MGF; Mechano growth factor; MGF; Somatomedia C; Somatomedin C; IGF1_HUMAN.
研究領(lǐng)域	細胞生物發(fā)育生物學(xué) 信號轉(zhuǎn)導(dǎo) 生長因子和激素糖尿病
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應(yīng)	Human, Rat, (predicted: Mouse, Dog, Pig, Cow, Rabbit, Sheep, )
產(chǎn)品應(yīng)用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	7.7/21kDa
細胞定位	分泌型蛋白
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human IGF I:108-195/195
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009] Function: The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. Subcellular Location: Secreted. DISEASE: Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) [MIM:608747]. IGF1 deficiency is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation. Similarity: Belongs to the insulin family. SWISS: P05019 Gene ID: 3479 Database links: Entrez Gene: 3479 Human Omim: 147440 Human SwissProt: P05019 Human Unigene: 160562 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 胰島素樣生長因子1(IGF-1)是一種生長調(diào)節(jié)激素，由肝分泌并入血液循環(huán)的中性多肽，具有調(diào)節(jié)生長和代謝、胰島素樣及促細胞分裂的活性。